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Novel Mechanism for Buffering Dietary Salt in Humans: Effects of Salt Loading on Skin Sodium, Vascular Endothelial Growth Factor C, and Blood Pressure

High dietary sodium intake triggers increased blood pressure (BP). Animal studies show that dietary salt loading results in dermal Na(+) accumulation and lymphangiogenesis mediated by VEGF-C (vascular endothelial growth factor C), both attenuating the rise in BP. Our objective was to determine wheth...

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Detalles Bibliográficos
Autores principales: Selvarajah, Viknesh, Mäki-Petäjä, Kaisa M., Pedro, Liliana, Bruggraber, Sylvaine F.A., Burling, Keith, Goodhart, Anna K., Brown, Morris J., McEniery, Carmel M., Wilkinson, Ian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640984/
https://www.ncbi.nlm.nih.gov/pubmed/28974570
http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10003