Cancer Drug Addiction is Relayed by an ERK2-Dependent Phenotype Switch

Drug addiction denotes the dependency of tumors on the same therapeutic drugs to which they have acquired resistance. Observations from cultured cells1–3, animal models4 and patients5–7 raise the possibility that cancer drug addiction can instigate a potential cancer vulnerability, which may be used...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Xiangjun, Kuilman, Thomas, Shahrabi, Aida, Boshuizen, Julia, Kemper, Kristel, Song, Ji-Ying, Niessen, Hans W.M., Rozeman, Elisa A., Geukes Foppen, Marnix H., Blank, Christian U., Peeper, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640985/
https://www.ncbi.nlm.nih.gov/pubmed/28976960
http://dx.doi.org/10.1038/nature24037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640985/
https://www.ncbi.nlm.nih.gov/pubmed/28976960
http://dx.doi.org/10.1038/nature24037

Ejemplares similares