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TORC1 Organised in Inhibited Domains (TOROIDs) regulate TORC1 activity

The Target of Rapamycin (TOR) is a eukaryotic serine/threonine protein kinase that functions in two distinct complexes, TORC1 and TORC2, to regulate growth and metabolism1,2. GTPases, responding to signals generated by abiotic stressors, nutrients, and, in metazoans, growth factors, play an importan...

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Detalles Bibliográficos
Autores principales: Prouteau, Manoël, Desfosses, Ambroise, Sieben, Christian, Bourgoint, Clélia, Mozaffari, Nour Lydia, Demurtas, Davide, Mitra, Alok K., Guichard, Paul, Manley, Suliana, Loewith, Robbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640987/
https://www.ncbi.nlm.nih.gov/pubmed/28976958
http://dx.doi.org/10.1038/nature24021