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Selective DNA methylation in cancers controls collateral damage induced by large structural variations
Chromosomal instability is a hallmark of human cancers, and is characterized by large structural variations in the genome. Such large structural variations are expected to create intrinsic collateral stress due to gene dosage changes in many genes that are co-deleted or co-amplified in large chromos...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641056/ https://www.ncbi.nlm.nih.gov/pubmed/29069713 http://dx.doi.org/10.18632/oncotarget.10487 |