Cargando…

Selective DNA methylation in cancers controls collateral damage induced by large structural variations

Chromosomal instability is a hallmark of human cancers, and is characterized by large structural variations in the genome. Such large structural variations are expected to create intrinsic collateral stress due to gene dosage changes in many genes that are co-deleted or co-amplified in large chromos...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohanty, Vakul, Akmamedova, Ogulsheker, Komurov, Kakajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641056/
https://www.ncbi.nlm.nih.gov/pubmed/29069713
http://dx.doi.org/10.18632/oncotarget.10487