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MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa

The mucus layer in the intestine affects several aspects of intestinal biology, encompassing physical, chemical protection, immunomodulation and growth, thus contributing to homeostasis. Mice with genetic inactivation of the Muc2 gene, encoding the MUC2 mucin, the major protein component of mucus, e...

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Detalles Bibliográficos
Autores principales: Tadesse, Selamawit, Corner, Georgia, Dhima, Elena, Houston, Michele, Guha, Chandan, Augenlicht, Leonard, Velcich, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641062/
https://www.ncbi.nlm.nih.gov/pubmed/29069719
http://dx.doi.org/10.18632/oncotarget.16886