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Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair

Homologous recombination (HR) enables precise DNA repair after DNA double strand breaks (DSBs) using identical sequence templates, whereas homeologous recombination (HeR) uses only partially homologous sequences. Homeologous recombination introduces mutations through gene conversion and genomic dele...

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Detalles Bibliográficos
Autores principales: Jahid, Sohail, Sun, Jian, Gelincik, Ozkan, Blecua, Pedro, Edelmann, Winfried, Kucherlapati, Raju, Zhou, Kathy, Jasin, Maria, Gümüş, Zeynep H., Lipkin, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641073/
https://www.ncbi.nlm.nih.gov/pubmed/29069730
http://dx.doi.org/10.18632/oncotarget.17776