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Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair
Homologous recombination (HR) enables precise DNA repair after DNA double strand breaks (DSBs) using identical sequence templates, whereas homeologous recombination (HeR) uses only partially homologous sequences. Homeologous recombination introduces mutations through gene conversion and genomic dele...
Autores principales: | Jahid, Sohail, Sun, Jian, Gelincik, Ozkan, Blecua, Pedro, Edelmann, Winfried, Kucherlapati, Raju, Zhou, Kathy, Jasin, Maria, Gümüş, Zeynep H., Lipkin, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641073/ https://www.ncbi.nlm.nih.gov/pubmed/29069730 http://dx.doi.org/10.18632/oncotarget.17776 |
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