Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

Pediatric high grade glioma (pHGGs), including sus-tentorial and diffuse intrinsic pontine gliomas, are known to have a very dismal prognosis. For instance, even an increased knowledge on molecular biology driving this brain tumor entity, there is no treatment able to cure those patients. Therefore,...

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Detalles Bibliográficos
Autores principales: Nguyen, Aurélia, Moussallieh, François Marie, Mackay, Alan, Cicek, A. Ercument, Coca, Andres, Chenard, Marie Pierre, Weingertner, Noelle, Lhermitte, Benoit, Letouzé, Eric, Guérin, Eric, Pencreach, Erwan, Jannier, Sarah, Guenot, Dominique, Namer, Izzie Jacques, Jones, Chris, Entz-Werlé, Natacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641075/
https://www.ncbi.nlm.nih.gov/pubmed/29069732
http://dx.doi.org/10.18632/oncotarget.16500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641075/
https://www.ncbi.nlm.nih.gov/pubmed/29069732
http://dx.doi.org/10.18632/oncotarget.16500

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