WX-132-18B, a novel microtubule inhibitor, exhibits promising anti-tumor effects

Cancer drug researchers have been seeking microtubule-inhibiting agents (MIAs) with higher bioactivity and lower toxicity than currently marketed drugs. WX-132-18B, a novel structural compound synthesized at our institute, specifically bound to the colchicine-binding site on tubulin rather than the...

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Detalles Bibliográficos
Autores principales: Guan, Fang, Ding, Rui, Zhang, Qi, Chen, Wei, Li, Feifei, Long, Long, Li, Wei, Li, Linna, Yang, Dexuan, Xie, Lan, Yuan, Shoujun, Wang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641089/
https://www.ncbi.nlm.nih.gov/pubmed/29069746
http://dx.doi.org/10.18632/oncotarget.17710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641089/
https://www.ncbi.nlm.nih.gov/pubmed/29069746
http://dx.doi.org/10.18632/oncotarget.17710

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