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Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis

Metastasis is the major dominant reason for poor prognosis of hepatocellular carcinoma (HCC) after surgical treatment. However, the molecular mechanism of metastasis has not been well characterzied. Here, we report a novel function of Barx homeobox1 (Barx1) in inhibiting HCC invasion and metastasis....

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Detalles Bibliográficos
Autores principales: Wang, Guodong, Liu, Jian, Cai, Yi, Chen, Jie, Xie, Wenbing, Kong, Xiangqian, Huang, Wenjie, Guo, Hao, Zhao, Xiaodi, Lu, Yuanyuan, Niu, Lu, Li, Xiaowei, Zhang, Haijia, Lei, Chao, Lei, Zhijie, Yin, Jipeng, Hu, Hao, Yu, Fan, Nie, Yongzhan, Xia, Limin, Wu, Kaichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641096/
https://www.ncbi.nlm.nih.gov/pubmed/29069753
http://dx.doi.org/10.18632/oncotarget.18288