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Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer

Circulating Tumour Cells (CTCs) and circulating tumour DNA (ctDNA) represent a non-invasive liquid biopsy approach for the follow-up and therapy management of cancer patients. We evaluated whether DNA methylation status in CTCs and ctDNA is comparable and whether it reflects the status of primary tu...

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Detalles Bibliográficos
Autores principales: Chimonidou, Maria, Strati, Areti, Malamos, Nikos, Kouneli, Sophia, Georgoulias, Vassilis, Lianidou, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641111/
https://www.ncbi.nlm.nih.gov/pubmed/29069768
http://dx.doi.org/10.18632/oncotarget.18679