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Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer

Drug repositioning is an alternative strategy redirecting existing drugs for new disease. We have previously reported an antitumor effect of statins, antidyslipidemic drugs, on ovarian cancer in vitro and in vivo. In this study, we investigated the antitumor effects of other mevalonate pathway inhib...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yusuke, Kashima, Hiroyasu, Rahmanto, Yohan Suryo, Banno, Kouji, Yu, Yu, Matoba, Yusuke, Watanabe, Keiko, Iijima, Moito, Takeda, Takashi, Kunitomi, Haruko, Iida, Miho, Adachi, Masataka, Nakamura, Kanako, Tsuji, Kosuke, Masuda, Kenta, Nomura, Hiroyuki, Tominaga, Eiichiro, Aoki, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641118/
https://www.ncbi.nlm.nih.gov/pubmed/29069775
http://dx.doi.org/10.18632/oncotarget.20046