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Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer
Colorectal cancer (CRC) develops from accumulated mutations. However, which gene determines the malignant transformation from adenoma to carcinoma is still uncertain. Fifty-three formalin fixed paraffin-embedded polyps that had pathological findings from patients with hyperplasia, adenomatous, and t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641135/ https://www.ncbi.nlm.nih.gov/pubmed/29069792 http://dx.doi.org/10.18632/oncotarget.20376 |