Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function

The tumor suppressor BAP1 associates with ASXL1/2 to form the core Polycomb complex PR-DUB, which catalyzes the removal of mono-ubiquitin from several substrates including histone H2A. This complex also mediates the poly-deubiquitination of HCFC1, OGT and PCG1-α, preventing them from proteasomal deg...

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Detalles Bibliográficos
Autores principales: Hebert, Lucie, Bellanger, Dorine, Guillas, Chloé, Campagne, Antoine, Dingli, Florent, Loew, Damarys, Fievet, Alice, Jacquemin, Virginie, Popova, Tatiana, Jean, Didier, Mechta-Grigoriou, Fatima, Margueron, Raphaël, Stern, Marc-Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641149/
https://www.ncbi.nlm.nih.gov/pubmed/29069806
http://dx.doi.org/10.18632/oncotarget.19872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641149/
https://www.ncbi.nlm.nih.gov/pubmed/29069806
http://dx.doi.org/10.18632/oncotarget.19872

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