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RPN2 promotes colorectal cancer cell proliferation through modulating the glycosylation status of EGFR

Various studies have found that silencing ribophorin II (RPN2) inhibits cell growth in several cancers. However, the underlying mechanism by which RPN2 regulates cancer cell proliferation remains unclear. Herein, we reveal that downregulation of RPN2, which may be a crucial regulator of N-linked gly...

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Detalles Bibliográficos
Autores principales: Li, Haiping, Al-Japairai, K, Tao, Yong, Xiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641158/
https://www.ncbi.nlm.nih.gov/pubmed/29069815
http://dx.doi.org/10.18632/oncotarget.20005