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Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells

Hepatocellular carcinoma (HCC) is one of the most serious cancers, with rapid progression and high mortality. However, chemotherapy of HCC is hindered by multi-drug resistance (MDR). It is urgent, therefore, to explore new approaches for overcoming MDR of HCC cells. Ubenimex, an inhibitor of CD13, h...

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Detalles Bibliográficos
Autores principales: Guo, Qie, Sui, Zhong-Guo, Xu, Wen, Quan, Xiang-Hua, Sun, Jia-Lin, Li, Xiao, Ji, Hong-Yan, Jing, Fan-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641159/
https://www.ncbi.nlm.nih.gov/pubmed/29069816
http://dx.doi.org/10.18632/oncotarget.20194