miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3

Tumor recurrence by obtaining chemoresistance is a major obstacle to treating ovarian cancer. By TargetScan database and a luciferase reporter assay, we identified miR-150 directly targets Notch3, which is a key oncogene in ovarian cancer. We, therefore, investigated the role of miR-150 in ovarian c...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hoen, Jeong, Ju-Yeon, Park, Ju-Yeon, Kim, Se-Wha, Heo, Jin Hyung, Kang, Haeyoun, Kim, Gwangil, An, Hee Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641169/
https://www.ncbi.nlm.nih.gov/pubmed/29069826
http://dx.doi.org/10.18632/oncotarget.20348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641169/
https://www.ncbi.nlm.nih.gov/pubmed/29069826
http://dx.doi.org/10.18632/oncotarget.20348

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