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Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells

Cancer cachexia is a result of increased protein degradation and decreased protein synthesis. The multifunctional circulating hormone ghrelin promotes synthesis and inhibits degradation of muscle protein, but its mechanism of action is not fully understood. Here, we investigated whether co-culturing...

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Detalles Bibliográficos
Autores principales: Zeng, Xianliang, Chen, Sizeng, Yang, Yang, Ke, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641175/
https://www.ncbi.nlm.nih.gov/pubmed/29069832
http://dx.doi.org/10.18632/oncotarget.20531