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Germline mutations in pancreatic cancer and potential new therapeutic options

Due to short-lived treatment responses in unresectable disease, pancreatic ductal adenocarcinoma (PDAC) continues to be one of the deadliest cancers. There is availability of new information about germline and sporadic mutations in the deoxyribonucleic acid (DNA) damage repair pathway in PDAC in rec...

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Detalles Bibliográficos
Autores principales: Pihlak, Rille, Valle, Juan W., McNamara, Mairéad G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641209/
https://www.ncbi.nlm.nih.gov/pubmed/29069866
http://dx.doi.org/10.18632/oncotarget.17291