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Reducing Extracellular Ca(2+) Induces Adenosine Release via Equilibrative Nucleoside Transporters to Provide Negative Feedback Control of Activity in the Hippocampus
Neural circuit activity increases the release of the purine neuromodulator adenosine into the extracellular space leading to A(1) receptor activation and negative feedback via membrane hyperpolarization and inhibition of transmitter release. Adenosine can be released by a number of different mechani...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641293/ https://www.ncbi.nlm.nih.gov/pubmed/29066955 http://dx.doi.org/10.3389/fncir.2017.00075 |