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Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy

Neuropilins (NRPs) are non-tyrosine kinase cell surface glycoproteins expressed in all vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 (NRP1) and neuropilin-2 (NRP2), mainly act as coreceptors for class III Semaphorins and for members of the vascular endotheli...

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Detalles Bibliográficos
Autores principales: Roy, Sohini, Bag, Arup K., Singh, Rakesh K., Talmadge, James E., Batra, Surinder K., Datta, Kaustubh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641316/
https://www.ncbi.nlm.nih.gov/pubmed/29067024
http://dx.doi.org/10.3389/fimmu.2017.01228