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Exoenzyme T Plays a Pivotal Role in the IFN-γ Production after Pseudomonas Challenge in IL-12 Primed Natural Killer Cells

Pseudomonas aeruginosa (PA) expresses the type III secretion system (T3SS) and effector exoenzymes that interfere with intracellular pathways. Natural killer (NK) cells play a key role in antibacterial immunity and their activation is highly dependent on IL-12 produced by myeloid cells. We studied P...

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Detalles Bibliográficos
Autores principales: Vourc’h, Mickael, Roquilly, Antoine, Broquet, Alexis, David, Gaelle, Hulin, Philippe, Jacqueline, Cedric, Caillon, Jocelyne, Retiere, Christelle, Asehnoune, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641345/
https://www.ncbi.nlm.nih.gov/pubmed/29067027
http://dx.doi.org/10.3389/fimmu.2017.01283