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Connexin43- and Pannexin-Based Channels in Neuroinflammation and Cerebral Neuropathies

Connexins (Cx) are largely represented in the central nervous system (CNS) with 11 Cx isoforms forming intercellular channels. Moreover, in the CNS, Cx43 can form hemichannels (HCs) at non-junctional membrane as does the related channel-forming Pannexin1 (Panx1) and Panx2. Opening of Panx1 channels...

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Detalles Bibliográficos
Autores principales: Sarrouilhe, Denis, Dejean, Catherine, Mesnil, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641369/
https://www.ncbi.nlm.nih.gov/pubmed/29066951
http://dx.doi.org/10.3389/fnmol.2017.00320