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Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression

The FGFR1-5-HT1A heteroreceptor complexes are involved in neuroplasticity in the rat hippocampus and in the mesencephalic raphe 5-HT nerve cells. There exists a 5-HT1A protomer enhancement of FGFR1 protomer signaling. Acute and 10 day treatment with intracerebroventricular (i.c.v.) FGF-2 and the 5-H...

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Detalles Bibliográficos
Autores principales: Borroto-Escuela, Dasiel O., DuPont, Caitlin M., Li, Xiang, Savelli, David, Lattanzi, Davide, Srivastava, Ipsit, Narváez, Manuel, Di Palma, Michael, Barbieri, Elisa, Andrade-Talavera, Yuniesky, Cuppini, Riccardo, Odagaki, Yuji, Palkovits, Miklos, Ambrogini, Patrizia, Lindskog, Maria, Fuxe, Kjell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641403/
https://www.ncbi.nlm.nih.gov/pubmed/29066953
http://dx.doi.org/10.3389/fncel.2017.00309