Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation

Changes in synaptic excitability and reduced brain metabolism are among the earliest detectable alterations associated with the development of Alzheimer’s disease (AD). Stimulation of synaptic activity has been shown to be protective in models of AD beta-amyloidosis. Remarkably, deep brain stimulati...

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Detalles Bibliográficos
Autores principales: Akwa, Yvette, Gondard, Elise, Mann, Amandeep, Capetillo-Zarate, Estibaliz, Alberdi, Elena, Matute, Carlos, Marty, Serge, Vaccari, Thomas, Lozano, Andres M., Baulieu, Etienne, Tampellini, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641448/
https://www.ncbi.nlm.nih.gov/pubmed/28696431
http://dx.doi.org/10.1038/mp.2017.142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641448/
https://www.ncbi.nlm.nih.gov/pubmed/28696431
http://dx.doi.org/10.1038/mp.2017.142

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