Cargando…

Mitochondrial ATP Depletion Disrupts Caco-2 Monolayer Integrity and Internalizes Claudin 7

Objective: In vivo studies suggest that intestinal barrier integrity is dependent on mitochondrial ATP production. Here, we aim to provide mechanistic support, using an in vitro model mimicking the oxidative in vivo situation. Methods: Human Caco-2 cells were cultured for 10 days in culture flasks o...

Descripción completa

Detalles Bibliográficos
Autores principales:	JanssenDuijghuijsen, Lonneke M., Grefte, Sander, de Boer, Vincent C. J., Zeper, Lara, van Dartel, Dorien A. M., van der Stelt, Inge, Bekkenkamp-Grovenstein, Melissa, van Norren, Klaske, Wichers, Harry J., Keijer, Jaap
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641570/ https://www.ncbi.nlm.nih.gov/pubmed/29075202 http://dx.doi.org/10.3389/fphys.2017.00794

Ejemplares similares

Endurance Exercise Increases Intestinal Uptake of the Peanut Allergen Ara h 6 after Peanut Consumption in Humans
por: JanssenDuijghuijsen, Lonneke M., et al.
Publicado: (2017)

The effect of endurance exercise on intestinal integrity in well‐trained healthy men
por: JanssenDuijghuijsen, Lonneke M., et al.
Publicado: (2016)

The female mouse is resistant to mild vitamin B(3) deficiency
por: van der Stelt, Inge, et al.
Publicado: (2021)

Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3
por: Shi, Wenbiao, et al.
Publicado: (2019)

High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet
por: Shi, Wenbiao, et al.
Publicado: (2019)

Evaluating Brewers’ Spent Grain Protein Isolate Postprandial Amino Acid Uptake Kinetics: A Randomized, Cross-Over, Double-Blind Controlled Study
por: Ummels, Meeke, et al.
Publicado: (2023)

Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice
por: van Dijk, Miriam, et al.
Publicado: (2016)

The Effect of Tomatine on Gene Expression and Cell Monolayer Integrity in Caco-2
por: Arena, Mattia P., et al.
Publicado: (2018)

Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular innervation
por: Song, Jingyi, et al.
Publicado: (2023)

Apical acidity decreases inhibitory effect of omeprazole on Mg(2+) absorption and claudin-7 and -12 expression in Caco-2 monolayers
por: Thongon, Narongrit, et al.
Publicado: (2012)

Mycotoxins: Biotransformation and Bioavailability Assessment Using Caco-2 Cell Monolayer
por: Tran, Van Nguyen, et al.
Publicado: (2020)

Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet
por: Shi, Wenbiao, et al.
Publicado: (2017)

Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2019)

Alpha-Gal on the Protein Surface Hampers Transcytosis through the Caco-2 Monolayer
por: Krstić Ristivojević, Maja, et al.
Publicado: (2020)

Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity
por: Pires, Cristiana L., et al.
Publicado: (2021)

Mito-Nuclear Communication by Mitochondrial Metabolites and Its Regulation by B-Vitamins
por: Janssen, Joëlle J. E., et al.
Publicado: (2019)

DPA shows comparable chemotherapy sensitizing effects as EPA upon cellular incorporation in tumor cells
por: Dijk, Francina J., et al.
Publicado: (2019)

The Use of Proton Pump Inhibitors May Increase Symptoms of Muscle Function Loss in Patients with Chronic Illnesses
por: Vinke, Paulien, et al.
Publicado: (2020)

Effects of whole-body vibration training in a cachectic C26 mouse model
por: van der Ende, Miranda, et al.
Publicado: (2021)

Metabolic Response of Visceral White Adipose Tissue of Obese Mice Exposed for 5 Days to Human Room Temperature Compared to Mouse Thermoneutrality
por: van der Stelt, Inge, et al.
Publicado: (2017)

Increasing quality of life in pulmonary arterial hypertension: is there a role for nutrition?
por: Vinke, Paulien, et al.
Publicado: (2018)

Replacing Part of Glucose with Galactose in the Postweaning Diet Protects Female But Not Male Mice from High-Fat Diet–Induced Adiposity in Later Life
por: Bouwman, Lianne M S, et al.
Publicado: (2019)

Peptide Release after Simulated Infant In Vitro Digestion of Dry Heated Cow’s Milk Protein and Transport of Potentially Immunoreactive Peptides across the Caco-2 Cell Monolayer
por: Zenker, Hannah E., et al.
Publicado: (2020)

Physicochemical Properties of Lutein-Loaded Microcapsules and Their Uptake via Caco-2 Monolayers
por: Zhao, Tong, et al.
Publicado: (2018)

Kinetic analysis of transcellular passage of the cobalamin–transcobalamin complex in Caco-2 monolayers
por: Juul, Christian B., et al.
Publicado: (2019)

Permeability of the Cyanotoxin Microcystin-RR across a Caco-2 Cells Monolayer
por: Henri, Jérôme, et al.
Publicado: (2021)

Galactose in the Post-Weaning Diet Programs Improved Circulating Adiponectin Concentrations and Skeletal Muscle Insulin Signaling
por: Sun, Peixin, et al.
Publicado: (2022)

Polystyrene Microplastics of Varying Sizes and Shapes Induce Distinct Redox and Mitochondrial Stress Responses in a Caco-2 Monolayer
por: Saenen, Nelly D., et al.
Publicado: (2023)

Bioavailability of Echinacea Constituents: Caco-2 Monolayers and Pharmacokinetics of the Alkylamides and Caffeic Acid Conjugates
por: Matthias, Anita, et al.
Publicado: (2005)

Effect of Chum Salmon Egg Lectin on Tight Junctions in Caco-2 Cell Monolayers
por: Nemoto, Ryo, et al.
Publicado: (2015)

Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers
por: Pérez-Sánchez, Almudena, et al.
Publicado: (2019)

Transport Mechanisms of Polymannuronic Acid and Polyguluronic Acid Across Caco-2 Cell Monolayers
por: Wang, Yu, et al.
Publicado: (2020)

Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers
por: Wang, Yi, et al.
Publicado: (2022)

Unraveling the intestinal epithelial barrier in cyanotoxin microcystin-treated Caco-2 cell monolayers
por: Kaak, Jan-Leo, et al.
Publicado: (2022)

No Adverse Programming by Post‐Weaning Dietary Fructose of Body Weight, Adiposity, Glucose Tolerance, or Metabolic Flexibility
por: Bouwman, Lianne M. S., et al.
Publicado: (2017)

Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model
por: Vinke, Paulien, et al.
Publicado: (2019)

Transepithelial Transport and Metabolism of Boronated Dipeptides Across Caco-2 and HCT-8 Cell Monolayers
por: Elkins, Amy L., et al.
Publicado: (1996)

Fatty acids modulate the expression levels of key proteins for cholesterol absorption in Caco-2 monolayer
por: Yang, Fang, et al.
Publicado: (2018)

Predicting apparent passive permeability of Caco-2 and MDCK cell-monolayers: A mechanistic model
por: Bittermann, Kai, et al.
Publicado: (2017)

Antihypertensive Effect in Vivo of QAGLSPVR and Its Transepithelial Transport Through the Caco-2 Cell Monolayer
por: Sun, Liping, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_btoq1tooqjjo8agene5shnde44