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Overcoming Obstacles to Drug Repositioning in Japan

Drug repositioning (DR) is the process of identifying new indications for existing drugs. DR usually focuses on drugs that have cleared phase-I safety trials but has yet to show efficacy for the intended indication. Therefore, DR can probably skip the preclinical and phase-I study, which can reduce...

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Detalles Bibliográficos
Autores principales: Nishimura, Yuhei, Tagawa, Masaaki, Ito, Hideki, Tsuruma, Kazuhiro, Hara, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641581/
https://www.ncbi.nlm.nih.gov/pubmed/29075191
http://dx.doi.org/10.3389/fphar.2017.00729