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Overcoming Obstacles to Drug Repositioning in Japan
Drug repositioning (DR) is the process of identifying new indications for existing drugs. DR usually focuses on drugs that have cleared phase-I safety trials but has yet to show efficacy for the intended indication. Therefore, DR can probably skip the preclinical and phase-I study, which can reduce...
Autores principales: | Nishimura, Yuhei, Tagawa, Masaaki, Ito, Hideki, Tsuruma, Kazuhiro, Hara, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641581/ https://www.ncbi.nlm.nih.gov/pubmed/29075191 http://dx.doi.org/10.3389/fphar.2017.00729 |
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