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Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine

OBJECTIVES: To identify sub-populations of intestinal preproglucagon-expressing (PPG) cells producing Glucagon-like Peptide-1, and their associated expression profiles of sensory receptors, thereby enabling the discovery of therapeutic strategies that target these cell populations for the treatment...

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Detalles Bibliográficos
Autores principales: Glass, Leslie L., Calero-Nieto, Fernando J., Jawaid, Wajid, Larraufie, Pierre, Kay, Richard G., Göttgens, Berthold, Reimann, Frank, Gribble, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641633/
https://www.ncbi.nlm.nih.gov/pubmed/29031728
http://dx.doi.org/10.1016/j.molmet.2017.07.014