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Na(v)1.8 neurons are involved in limiting acute phase responses to dietary fat

OBJECTIVE AND METHODS: Metabolic viscera and their vasculature are richly innervated by peripheral sensory neurons. Here, we examined the metabolic and inflammatory profiles of mice with selective ablation of all Na(v)1.8-expressing primary afferent neurons. RESULTS: While mice lacking sensory neuro...

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Detalles Bibliográficos
Autores principales: Udit, Swalpa, Burton, Michael, Rutkowski, Joseph M., Lee, Syann, Bookout, Angie L., Scherer, Philipp E., Elmquist, Joel K., Gautron, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641637/
https://www.ncbi.nlm.nih.gov/pubmed/29031710
http://dx.doi.org/10.1016/j.molmet.2017.07.012