A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA

Bacterial signaling systems such as protein kinases and quorum sensing have become increasingly attractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resistance. The family of bacterial Penicillin-binding-protein And Serine/Threonine kinase-Associated (P...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaenzer, Adam J., Wlodarchak, Nathan, Drewry, David H., Zuercher, William J., Rose, Warren E., Striker, Rob, Sauer, John-Demian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641865/
https://www.ncbi.nlm.nih.gov/pubmed/28821610
http://dx.doi.org/10.1074/jbc.M117.808600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641865/
https://www.ncbi.nlm.nih.gov/pubmed/28821610
http://dx.doi.org/10.1074/jbc.M117.808600

Ejemplares similares