Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates

We previously showed that hyperoxia in vitro negatively affects beta cells of the rat. Here, we tested for possible clinical significance as well as mitochondrial interactions by hyperoxia, using human islets (function and viability), INS‐1 832/13 cells (mitochondrial metabolism), and mouse neonates...

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Detalles Bibliográficos
Autores principales: Hals, Ingrid, Ohki, Tsuyoshi, Singh, Rinku, Ma, Zuheng, Björklund, Anneli, Balasuriya, Chandima, Scholz, Hanne, Grill, Valdemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641934/
https://www.ncbi.nlm.nih.gov/pubmed/29038359
http://dx.doi.org/10.14814/phy2.13447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641934/
https://www.ncbi.nlm.nih.gov/pubmed/29038359
http://dx.doi.org/10.14814/phy2.13447

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