Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages

Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to defective autophagy, causing continued system...

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Detalles Bibliográficos
Autores principales: Shrestha, Chandra L., Assani, Kaivon D., Rinehardt, Hannah, Albastroiu, Florentina, Zhang, Shuzhong, Shell, Richard, Amer, Amal O., Schlesinger, Larry S., Kopp, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642023/
https://www.ncbi.nlm.nih.gov/pubmed/28982193
http://dx.doi.org/10.1371/journal.pone.0186169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642023/
https://www.ncbi.nlm.nih.gov/pubmed/28982193
http://dx.doi.org/10.1371/journal.pone.0186169

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