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Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages
Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to defective autophagy, causing continued system...
Autores principales: | Shrestha, Chandra L., Assani, Kaivon D., Rinehardt, Hannah, Albastroiu, Florentina, Zhang, Shuzhong, Shell, Richard, Amer, Amal O., Schlesinger, Larry S., Kopp, Benjamin T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642023/ https://www.ncbi.nlm.nih.gov/pubmed/28982193 http://dx.doi.org/10.1371/journal.pone.0186169 |
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