Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype

The aim of this study was to compare the hemostatic efficacy of recombinant factor VIII Fc (rFVIIIFc) (Eloctate) and Advate by ex-vivo rotation thromboelastometry (ROTEM) of whole blood and to explore potential ROTEM parameters that may be more predictive of a patient's bleeding tendency than p...

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Detalles Bibliográficos
Autores principales: Driessler, Frank, Miguelino, Maricel G., Pierce, Glenn F., Peters, Robert T., Sommer, Jurg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams And Wilkins 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642334/
https://www.ncbi.nlm.nih.gov/pubmed/28486277
http://dx.doi.org/10.1097/MBC.0000000000000638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642334/
https://www.ncbi.nlm.nih.gov/pubmed/28486277
http://dx.doi.org/10.1097/MBC.0000000000000638

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