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HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

Adult T-cell leukemia/lymphoma (ATL) is an aggressive T cell malignancy that occurs in HTLV-1 infected patients. Most ATL patients develop osteolytic lesions and hypercalcemia of malignancy, causing severe skeletal related complications and reduced overall survival. The HTLV-1 virus encodes 2 viral...

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Detalles Bibliográficos
Autores principales: Esser, Alison K., Rauch, Daniel A., Xiang, Jingyu, Harding, John C., Kohart, Nicole A., Ross, Michael H., Su, Xinming, Wu, Kevin, Huey, Devra, Xu, Yalin, Vij, Kiran, Green, Patrick L., Rosol, Thomas J., Niewiesk, Stefan, Ratner, Lee, Weilbaecher, Katherine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642476/
https://www.ncbi.nlm.nih.gov/pubmed/29050201
http://dx.doi.org/10.18632/oncotarget.20565