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HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T cell malignancy that occurs in HTLV-1 infected patients. Most ATL patients develop osteolytic lesions and hypercalcemia of malignancy, causing severe skeletal related complications and reduced overall survival. The HTLV-1 virus encodes 2 viral...
Autores principales: | Esser, Alison K., Rauch, Daniel A., Xiang, Jingyu, Harding, John C., Kohart, Nicole A., Ross, Michael H., Su, Xinming, Wu, Kevin, Huey, Devra, Xu, Yalin, Vij, Kiran, Green, Patrick L., Rosol, Thomas J., Niewiesk, Stefan, Ratner, Lee, Weilbaecher, Katherine N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642476/ https://www.ncbi.nlm.nih.gov/pubmed/29050201 http://dx.doi.org/10.18632/oncotarget.20565 |
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