A small-molecule inhibitor targeting the AURKC–IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells

The Aurora kinases, Aurora A (AURKA), Aurora B (AURKB), and Aurora C (AURKC), are serine/threonine kinases required for the control of mitosis (AURKA and AURKB) or meiosis (AURKC). Several Aurora kinase inhibitors are being investigated as novel anticancer therapeutics. Recent studies demonstrated t...

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Detalles Bibliográficos
Autores principales: Han, Eun Hee, Min, Jin-Young, Yoo, Shin-Ae, Park, Sung-Joon, Choe, Yun-Jeong, Yun, Hee Sub, Lee, Zee-Won, Jin, Sun Woo, Kim, Hyung Gyun, Jeong, Hye Gwang, Kim, Hyun Kyoung, Kim, Nam Doo, Chung, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642509/
https://www.ncbi.nlm.nih.gov/pubmed/29050234
http://dx.doi.org/10.18632/oncotarget.18883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642509/
https://www.ncbi.nlm.nih.gov/pubmed/29050234
http://dx.doi.org/10.18632/oncotarget.18883

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