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A small-molecule inhibitor targeting the AURKC–IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells
The Aurora kinases, Aurora A (AURKA), Aurora B (AURKB), and Aurora C (AURKC), are serine/threonine kinases required for the control of mitosis (AURKA and AURKB) or meiosis (AURKC). Several Aurora kinase inhibitors are being investigated as novel anticancer therapeutics. Recent studies demonstrated t...
Autores principales: | Han, Eun Hee, Min, Jin-Young, Yoo, Shin-Ae, Park, Sung-Joon, Choe, Yun-Jeong, Yun, Hee Sub, Lee, Zee-Won, Jin, Sun Woo, Kim, Hyung Gyun, Jeong, Hye Gwang, Kim, Hyun Kyoung, Kim, Nam Doo, Chung, Young-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642509/ https://www.ncbi.nlm.nih.gov/pubmed/29050234 http://dx.doi.org/10.18632/oncotarget.18883 |
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