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NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer

Mutations in Kelch-like ECH-associated protein 1 (KEAP1) cause the aberrant activation of nuclear factor erythroid-derived 2-like 2 (NRF2), which leads to oncogenesis and drug resistance in lung cancer cells. Our study was designed to identify the genes involved in lung cancer progression targeted b...

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Detalles Bibliográficos
Autores principales: Namani, Akhileshwar, Cui, Qin Qin, Wu, Yihe, Wang, Hongyan, Wang, Xiu Jun, Tang, Xiuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642521/
https://www.ncbi.nlm.nih.gov/pubmed/29050246
http://dx.doi.org/10.18632/oncotarget.19349