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RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway

The Nm23 metastasis suppressor family is involved in physiological and pathological processes including tumorigenesis and metastasis. Although the inverse correlation of Nm23 level with tumor metastasis potential has been widely observed, the mechanisms that regulate the expression of Nm23 remain po...

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Detalles Bibliográficos
Autores principales: Li, Yuanjun, Song, Jiaxing, Tong, Yao, Chung, Sookja Kim, Wong, Yung H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642529/
https://www.ncbi.nlm.nih.gov/pubmed/29050254
http://dx.doi.org/10.18632/oncotarget.19509