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Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention

Alpha linolenic acid is an essential polyunsaturated fatty acid and is reported to have the anti-cancer potential with no defined hypothesis or mechanism/s. Henceforth present study was in-quested to validate the effect of alpha linolenic acid on mitochondrial apoptosis, hypoxic microenvironment and...

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Detalles Bibliográficos
Autores principales: Roy, Subhadeep, Rawat, Atul Kumar, Sammi, Shreesh Raj, Devi, Uma, Singh, Manjari, Gautam, Swetlana, Yadav, Rajnish Kumar, Rawat, Jitendra Kumar, Singh, Lakhveer, Ansari, Mohd. Nazam, Saeedan, Abdulaziz S., Pandey, Rakesh, Kumar, Dinesh, Kaithwas, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642536/
https://www.ncbi.nlm.nih.gov/pubmed/29050261
http://dx.doi.org/10.18632/oncotarget.19551