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Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention
Alpha linolenic acid is an essential polyunsaturated fatty acid and is reported to have the anti-cancer potential with no defined hypothesis or mechanism/s. Henceforth present study was in-quested to validate the effect of alpha linolenic acid on mitochondrial apoptosis, hypoxic microenvironment and...
Autores principales: | Roy, Subhadeep, Rawat, Atul Kumar, Sammi, Shreesh Raj, Devi, Uma, Singh, Manjari, Gautam, Swetlana, Yadav, Rajnish Kumar, Rawat, Jitendra Kumar, Singh, Lakhveer, Ansari, Mohd. Nazam, Saeedan, Abdulaziz S., Pandey, Rakesh, Kumar, Dinesh, Kaithwas, Gaurav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642536/ https://www.ncbi.nlm.nih.gov/pubmed/29050261 http://dx.doi.org/10.18632/oncotarget.19551 |
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