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Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling

Ovarian cancer is the most lethal gynaecological malignancy. Recurrence and subsequent resistance to chemotherapy have become major obstacles to treating these diseases. In the present study, we showed that a natural withanolide isolated from the plant Physalis pubescens L. (Solanaceae), Physapubesc...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaofeng, Huang, Lu, Xu, Wanwan, Chen, Xiaoyan, Shen, Yan, Zeng, Wenjie, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642541/
https://www.ncbi.nlm.nih.gov/pubmed/29050266
http://dx.doi.org/10.18632/oncotarget.19593