Cargando…

Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2

The small ubiquitin-related modifier (SUMO) system is essential for smooth progression of cell cycle at the G2/M phase. Many centromeric proteins are reversibly SUMOylated to ensure proper chromosome segregation at the mitosis. SUMOylation of centromeric Origin Recognition Complex subunit 2 (ORC2) a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ronghua, Liu, Fangming, Zhao, Yongxu, Wu, Dan, Chen, Lihan, Yeh, Edward T.H., Huang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642542/
https://www.ncbi.nlm.nih.gov/pubmed/29050267
http://dx.doi.org/10.18632/oncotarget.19594