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Reversible regulation of ORC2 SUMOylation by PIAS4 and SENP2

The small ubiquitin-related modifier (SUMO) system is essential for smooth progression of cell cycle at the G2/M phase. Many centromeric proteins are reversibly SUMOylated to ensure proper chromosome segregation at the mitosis. SUMOylation of centromeric Origin Recognition Complex subunit 2 (ORC2) a...

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Detalles Bibliográficos
Autores principales:	Wang, Ronghua, Liu, Fangming, Zhao, Yongxu, Wu, Dan, Chen, Lihan, Yeh, Edward T.H., Huang, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642542/ https://www.ncbi.nlm.nih.gov/pubmed/29050267 http://dx.doi.org/10.18632/oncotarget.19594

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