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A new donors’ CYP3A5 and recipients’ CYP3A4 cluster predicting tacrolimus disposition, and new-onset hypertension in Chinese liver transplant patients

AIM: The purpose of the current study was to investigate individualized therapy of tacrolimus (Tac), as well as complications after liver transplantation (LT) with the known genetic determinants and clinical factors. METHODS: In this retrospective study, two cohorts (n=170) from the China Liver Tran...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Zhang, Tao, Zhang, Xiaoqing, Ye, Ling, Gu, Haitao, Zhong, Lin, Sun, Hongcheng, Song, Chenlong, Peng, Zhihai, Fan, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642551/
https://www.ncbi.nlm.nih.gov/pubmed/29050276
http://dx.doi.org/10.18632/oncotarget.19606