SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts

SSeCKS/Gravin/AKAP12 (SSeCKS) is a kinase scaffolding protein known to suppress metastasis by attenuating tumor-intrinsic PKC- and Src-mediated signaling pathways [1]. In addition to downregulation in metastatic cells, in silico analyses identified SSeCKS downregulation in prostate or breast cancer-...

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Detalles Bibliográficos
Autores principales: Muramatsu, Masashi, Gao, Lingqiu, Peresie, Jennifer, Balderman, Benjamin, Akakura, Shin, Gelman, Irwin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642554/
https://www.ncbi.nlm.nih.gov/pubmed/29050279
http://dx.doi.org/10.18632/oncotarget.20092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642554/
https://www.ncbi.nlm.nih.gov/pubmed/29050279
http://dx.doi.org/10.18632/oncotarget.20092

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