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Effective antitumor peptide vaccines can induce severe autoimmune pathology

Immunotherapy has shown a tremendous success in treating cancer. Unfortunately, this success is frequently associated with severe autoimmune pathology. In this study, we used the transgenic RIP-gp mouse model to assess the antitumor therapeutic benefit of peptide vaccination while evaluating the pos...

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Detalles Bibliográficos
Autores principales: Sultan, Hussein, Trillo-Tinoco, Jimena, Rodriguez, Paulo, Celis, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642557/
https://www.ncbi.nlm.nih.gov/pubmed/29050282
http://dx.doi.org/10.18632/oncotarget.19688