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Omeprazole promotes carcinogenesis of fore-stomach in mice with co-stimulation of nitrosamine

OBJECTIVES: To investigate if oral omeprazole application induces cancers of fore and glandular stomach in mice. METHODS: A total of 66 eligible male mice were randomly divided into 6 groups, which were treated with control reagent, low (6 mg/kg) and high dose omeprazole (30 mg/kg), N-methyl-N’-nitr...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Qi, Dong-Jiang, He, Wei, Xu, A-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642558/
https://www.ncbi.nlm.nih.gov/pubmed/29050283
http://dx.doi.org/10.18632/oncotarget.19696